Review: Rotavirus disease – A zoonosis
PDF (Vietnamese)

Keywords

genome reassortment
rotavirus
zoonosis bệnh lây chung
rotavirus
tái sắp xếp gene

Abstract

A review of a significant number of works published on international media relating to some aspects of rotavirus (RV) infections in domesticated cattle, pigs, dogs, cats, goats and chickens (the species reared most commonly in Vietnam), as well as in humans, is presented to answer the question if the disease is zoonotic. The structure, replication processes, pathogenesis and immunity induction of the virus, the signs of the illness, and molecular epidemiology of the infection are demonstrated, helping to understand the resistance, transmission mechanism, and phylogenetic generation of the virus. This non-enveloped icosahedral virus possessing a genome consisting of 11 discrete double-stranded RNA fragments can transmit from one species of vertebrates to another, either in the original form of virions or through genetic material contribution in genome reassortment, e.g., the combination of discrete gene fragments of different type RV strains, forming new genome coding viral surface proteins adapting better to cell receptors of different host animal species.

https://doi.org/10.26459/hueunijard.v131i3D.6743
PDF (Vietnamese)

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