Non-hydrophilic components from roots of Vietnamese ginseng (Panax vietnamensis Ha & Grushv.)
Vol. 133 No. 1D (2024), Original Article
Vol. 133 No. 1D (2024)

Non-hydrophilic components from roots of Vietnamese ginseng (Panax vietnamensis Ha & Grushv.)

Original Article
https://doi.org/10.26459/hueunijns.v133i1D.7308
Published 2024-12-31
Thi Hoang Anh Nguyen
University of Medicine and Pharmacy, Vietnam National University – Hanoi (VNU), Hanoi, Vietnam
Thi Ngan Dang
University of Medicine and Pharmacy, Vietnam National University – Hanoi (VNU), Hanoi, Vietnam
Doan Manh Dung
Institute of Biotechnology and Environment, Tay Nguyen University, Buon Ma Thuot, Dak Lak, Vietnam
Thi Thanh Binh Nguyen
University of Medicine and Pharmacy, Vietnam National University – Hanoi (VNU), Hanoi, Vietnam
Ngoc Hieu Nguyen
Faculty of Pharmacy, PHENIKAA University, Hanoi 12116, Vietnam
Van Tuan Vu
Faculty of Pharmacy, PHENIKAA University, Hanoi 12116, Vietnam
Nguyen Huu Tung*
Faculty of Pharmacy, PHENIKAA University, Hanoi 12116, Vietnam
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Keywords

Vietnamese ginseng
Panax vietnamensis Ha & Grushv.
ginseng
falcarinol
20S-protopanaxatriol

How to Cite

1.
Nguyen THA, Dang TN, Manh Dung D, Nguyen TTB, Nguyen NH, Vu VT, Nguyen HT. Non-hydrophilic components from roots of Vietnamese ginseng (Panax vietnamensis Ha & Grushv.). hueuni-jns [Internet]. 2024Dec.31 [cited 2025Mar.18];133(1D):19-25. Available from: https://jos.hueuni.edu.vn/index.php/hujos-ns/article/view/7308
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Abstract

Vietnamese ginseng is a precious medicinal herb and contains various ginsenosides as the main components. We studied the less polar constituents of the title ginseng and isolated falcarinol (1) and 20S-protopanaxatriol (4) for the first time, along with two common phytosterols: β-sitosterol (2) and daucosterol (3). Their structures were elucidated with nuclear magnetic resonance (NMR) and mass spectrometry (MS) spectra and compared with the literature data. Falcarinol was obtained from the non-polar portion of the crude residue, with a high content. The occurrence of 20S-protopanaxatriol becomes evidence for similar biosynthesis of ginsenoside in Panax spp. The obtained results contributed partly to the phytochemical database of Vietnamese ginseng and the Panax genus.

https://doi.org/10.26459/hueunijns.v133i1D.7308
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