Development and validation of modified QuEChERS- GC/MS method for simultaneous determination of current-use pesticide residues in soil
Vol. 135 No. 1B (2026), Original Article
Vol. 135 No. 1B (2026)

Development and validation of modified QuEChERS- GC/MS method for simultaneous determination of current-use pesticide residues in soil

Original Article
https://doi.org/10.26459/hueunijns.v135i1B.8225
Published 2026-05-29
Thi Hong Nguyen
Faculty of Chemistry, University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Vietnam
Vinh Nhan Huynh
Phenikaa Hue mineral processing and investments one-member company limited. Plot CN15B, Phong Dien Industrial Zone, Phong Dinh Ward, Hue City, Vietnam
Ngoc Bang Thanh Trinh
Department of Chemistry, University of Sciences, Hue University, 77 Nguyen Hue St., Hue City, Vietnam
Thi Thanh Xuan Ngo
Hue City’s Centre for Testing Drugs, Cosmetics, and Foods, 17 Truong Dinh St., Hue City, Vietnam
Lam Son Le
Faculty of Chemistry, University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Vietnam
Duc Cuong Nguyen
University of Education, Hue University, Hue City, Vietnam
Dang Giang Chau Nguyen
Faculty of Chemistry, University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Vietnam
Thi Tuy Ngoc Huynh
Hue City’s Centre for Testing Drugs, Cosmetics, and Foods, 17 Truong Dinh St., Hue City, Vietnam
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Keywords

QuEChERS
pesticides
dispersive solid-phase extraction
Soil

How to Cite

1.
Nguyen TH, Huynh VN, Trinh NBT, Ngo TTX, Le LS, Nguyen DC, Nguyen DGC, Huynh TTN. Development and validation of modified QuEChERS- GC/MS method for simultaneous determination of current-use pesticide residues in soil. hueuni-jns [Internet]. 2026May29 [cited 2026Sep.22];135(1B):65-7. Available from: https://jos.hueuni.edu.vn/index.php/hujos-ns/article/view/8225
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Abstract

Pesticide residues in soil pose potential risks to ecosystems and human health, necessitating reliable and efficient analytical methods for their determination. This study developed and validated a modified QuEChERS-based extraction procedure combined with gas chromatography-mass spectrometry (GC/MS) for the simultaneous analysis of eight commonly used pesticides in soil, including herbicides, insecticides, and fungicides. Key extraction parameters were optimised for soil matrices, focusing on solvent composition and primary-secondary amine (PSA) clean-up levels. Optimal performance was achieved with 1% acetic acid in acetonitrile and 25 mg PSA per 1 mL of extract. The method was validated according to European Commission SANTE guidelines, demonstrating good linearity (R² > 0.99), low limits of detection (3–8 µg/kg), acceptable recoveries (69–114%), and satisfactory repeatability (RSD < 13%). The validated procedure was successfully applied to agricultural soil samples from central Vietnam, where residues of pretilachlor, fluazifop-p-butyl, and trifloxystrobin were detected. The results confirm that the proposed method is reliable, cost-effective, and suitable for routine monitoring of pesticide residues in soil.

https://doi.org/10.26459/hueunijns.v135i1B.8225
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