Steroids and flavone from the rhizomes of Homalomena pendula
Vol. 131 No. 1C (2022), Original Article
Vol. 131 No. 1C (2022)

Steroids and flavone from the rhizomes of Homalomena pendula

Original Article
https://doi.org/10.26459/hueunijns.v131i1C.6598
Published 2022-09-30
Nguyen Khanh Thuy Linh
University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Vietnam
Tran Ngan Thi
University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Vietnam
Nguyen Thi Ngoc Tram
University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Vietnam
Le Van Hau
University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Vietnam
Hoang Thi Nhu Hanh
University of Agriculture and Forestry, Hue University, 102 Phung Hung St., Hue, Vietnam
Nguyen Thi Hoai
University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Vietnam
Ho Viet Duc*
University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Vietnam
PDF (Vietnamese)

Keywords

Homalomena pendula, tangeretin , ergosterol peroxide, sitoindoside I Homalomena pendula, tangeretin , ergosterol peroxide, sitoindoside I

How to Cite

1.
Nguyễn KTL, Trần NT, Nguyễn TNT, Lê VH, Hoàng TNH, Nguyễn TH, Hồ V Đức. Steroids and flavone from the rhizomes of Homalomena pendula. hueuni-jns [Internet]. 2022Sep.30 [cited 2024Dec.22];131(1C):63-71. Available from: https://jos.hueuni.edu.vn/index.php/hujos-ns/article/view/6598
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Abstract

Phytochemical investigation of the rhizomes of Homalomena pendula resulted in the isolation of one flavone and three steroids. These compounds were determined as tangeretin (1), ergosterol peroxide (2), sitoindoside I (3), and stigmasterol (4) on the basis of 1D and 2D NMR data and in comparison with the available data in the literature. Compounds 1‒3 were found for the first time from the genus Homamomena. The n-hexane and ethyl acetate extracts show NO production inhibitory activity in RAW 264.7 macrophage cells with IC50 values of 46.8 and 75.52 µg·mL–1.

https://doi.org/10.26459/hueunijns.v131i1C.6598
PDF (Vietnamese)

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