In vitro antioxidant activity and content of bioactive compounds from Homalomena occulta
Vol. 133 No. 1B (2024), Original Article
Vol. 133 No. 1B (2024)

In vitro antioxidant activity and content of bioactive compounds from Homalomena occulta

Original Article
https://doi.org/10.26459/hueunijns.v133i1B.7256
Published 2024-06-27
Le Thuy Trang
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
Le Lam Son
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
Nguyen Van Dung
Dak Mil High School, Dak Mil, Dak Nong, Viet Nam
Ho Xuan Anh Vu
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
Nguyen Quang Man
University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Viet Nam
Tran Thanh Minh
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
Tran Thi Van Thi
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
Nguyen Viet Thang
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
Vo Thi Khanh Ly
Hue Medical College, 01 Nguyen Truong To St., Hue, Viet Nam
Nguyen Minh Nhung
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
Le Trung Hieu*
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
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Keywords

Homalomena occulta, antioxidant activity, polysaccharide, triterpenoids, total phenolic content, total flavonoid content.

How to Cite

1.
Le Thuy T, Le Lam S, Nguyen Van D, Ho Xuan AV, Nguyen Quang M, Tran Thanh M, Tran Thi Van T, Nguyen Viet T, Vo Thi Khanh L, Nguyen Minh N, Le Trung H. In vitro antioxidant activity and content of bioactive compounds from Homalomena occulta. hueuni-jns [Internet]. 2024Jun.27 [cited 2024Nov.22];133(1B):79-87. Available from: https://jos.hueuni.edu.vn/index.php/hujos-ns/article/view/7256
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Abstract

Homalomena occulta, a plant widely used in traditional Vietnamese medicine, was assessed for its antioxidant potential through DPPH radical scavenging and total antioxidant capacity methods. The results showed that Homalomena occulta exhibited significant antioxidant activities with a low IC50 value of 40.27 μg/mL, which is comparable to that of curcumin (38.50 μg/mL). Furthermore, the total antioxidant capacity of the Homalomena occulta extract was determined to be 77.48 ± 2.34 mg GA/g. To investigate the composition of the plant, various compounds including total phenolic, total flavonoid, polysaccharides, and triterpenoids were quantified using colorimetric methods with specific reagents. The content of phenolic compounds, flavonoid compounds, polysaccharides, and triterpenoids in Homalomena occulta was found to be 36.87 ± 0.42 GAE/g, 26.83 ± 0.29 mg QUE/g, 5.06 ± 0.06%, and 52.09 ± 1.77 mg Olenanoic/g, respectively. Notably, this study provides the first-ever report on the polysaccharide and total triterpenoid content of Homalomena occulta.

https://doi.org/10.26459/hueunijns.v133i1B.7256
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