SYNTHESIS AND BIOLOGICAL ACTIVITY EVALUATION OF SOME DERIVATIVES SYNTHESIZED FROM CURCUMIN AND CURCUMIN ANALOG
Vol. 126 No. 1B (2017), Original Article
Vol. 126 No. 1B (2017)

SYNTHESIS AND BIOLOGICAL ACTIVITY EVALUATION OF SOME DERIVATIVES SYNTHESIZED FROM CURCUMIN AND CURCUMIN ANALOG

Original Article
https://doi.org/10.26459/hueuni-jns.v126i1B.4139
Published 2017-07-15
Duong Quoc Hoan
Department of Chemistry, Hanoi National University of Education, A4, 136 Xuan Thuy, Cau Giay, Ha Noi, Viet Nam
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Keywords

thermodynamic
harmonic trap
ideal Fermi gas

How to Cite

1.
Hoan DQ. SYNTHESIS AND BIOLOGICAL ACTIVITY EVALUATION OF SOME DERIVATIVES SYNTHESIZED FROM CURCUMIN AND CURCUMIN ANALOG. hueuni-jns [Internet]. 2017Jul.15 [cited 2024Nov.23];126(1B):119-25. Available from: https://jos.hueuni.edu.vn/index.php/hujos-ns/article/view/4139
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Abstract

The acetohydrazides A5 containing an isoxazole ring and B5 containing an indazole ring were synthesized from the corresponding acetohydrazide derivatives with acetic anhydride in about 80% high yield. Also, two acetohydrazones B6 and B7 were driven from acetohydrazide B4 by condensation reaction. Bioactivity testes showed that none of them were active against on bacteria except acetohydrazones  B7 showing moderate reactivity against KB cancer cell line at IC50 = 57 mg/L.
https://doi.org/10.26459/hueuni-jns.v126i1B.4139
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