In vitro antioxidant activity and bioactive compounds from Calocybe indica
Vol. 130 No. 1D (2021), Original Article
Vol. 130 No. 1D (2021)

In vitro antioxidant activity and bioactive compounds from Calocybe indica

Original Article
https://doi.org/10.26459/hueunijns.v130i1D.6348
Published 2021-12-31
Nguyen Quang Man
University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Viet Nam
Le Lam Son
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
Nguyen Minh Nhung
Technical Centre for Quality Measurement Standards, Department of Science and Technology of Thua Thien Hue, Vy Da 7 Planning Area, Vy Da, Hue, Viet Nam
Nguyen Chinh Chien
Laboratory of Energy and Environmental Science, Institute of Research and Development, Duy Tan University, Da Nang, Vietnam 5Faculty of Environmental and Chemical Engineering, Duy Tan University, Da Nang, Vietnam
Ho Xuan Anh Vu
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
Nguyen Vinh Phu
University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Viet Nam
Tran Thanh Minh
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
Le Thuy Trang
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
Tran Thi Van Thi
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
Le Trung Hieu*
University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
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Keywords

Nấm Trắng Sữa Calocybe indica
antioxidant activity
polysaccharide
triterpenoid
total phenolics
total flavonoid

How to Cite

1.
Nguyen QM, Le LS, Nguyen MN, Nguyen CC, Ho XAV, Nguyen VP, Tran TM, Le TT, Tran TVT, Hieu LT. In vitro antioxidant activity and bioactive compounds from Calocybe indica. hueuni-jns [Internet]. 2021Dec.31 [cited 2024Nov.23];130(1D):15-22. Available from: https://jos.hueuni.edu.vn/index.php/hujos-ns/article/view/6348
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Abstract

Nowadays, the use of mushrooms in medicine is ubiquitous and has achieved particular success. The antioxidants in mushrooms can deactivate free radicals. This study assesses the antioxidant potential of mushroom Calocybe indica with the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging methods and the total antioxidant capacity. The mushroom’s ethanol extract exhibits acceptable activity with a low IC50 value (240.11 μg/mL), approximately 2.9 times lower than that of the mushroom Ophiocordyceps sobolifera extract. The ABTS scavenging rate of the extract is around 60% at 500 µg/mL, and the total antioxidant capacity is equivalent to 64.94 ± 1.03 mg of GA/g or 77.42 ± 0.42 μmol of AS/g.  The total phenolics, flavonoids, polysaccharides, and triterpenoids are equivalent to 29.33 ± 0.16 mg of GAE/g, 17.84 ± 0.11 mg of QUE/g (5.04 ± 0.04%), and 4.96 ± 0.04 mg of oleanolic acid/g, respectively. Specifically, the total triterpenoid content has been reported for the first time. The mushroom can have potential biomedical applications.

https://doi.org/10.26459/hueunijns.v130i1D.6348
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