Extraction and enrichment of flavonoid and evaluation of antioxidant activity of Passiflora foetida extract
Vol. 134 No. 1C (2025), Original Article
Vol. 134 No. 1C (2025)

Extraction and enrichment of flavonoid and evaluation of antioxidant activity of Passiflora foetida extract

Original Article
https://doi.org/10.26459/hueunijns.v134i1C.7753
Published 2025-06-17
Tran Phan Thi Diem
Mientrung Institute for Scientific Research, Vietnam National Museum of Nature, VAST, 321 Huynh Thuc Khang, Hue, Thua Thien Hue, Vietnam
Ha Tran Phuong
Mientrung Institute for Scientific Research, Vietnam National Museum of Nature, VAST, 321 Huynh Thuc Khang, Hue, Thua Thien Hue, Vietnam
Thi Thanh Tam Vu
Huu Dat Ton That
Mientrung Institute for Scientific Research, Vietnam National Museum of Nature, VAST, 321 Huynh Thuc Khang, Hue, Thua Thien Hue, Vietnam
Le Canh Viet Cuong*
Mientrung Institute for Scientific Research, Vietnam National Museum of Nature, VAST, 321 Huynh Thuc Khang, Hue, Thua Thien Hue, Vietnam
PDF (Vietnamese)

Keywords

Lạc tiên
hấp phụ
nhựa diaion HP20
hoạt tính chống oxy hóa Passiflora foetida L.
adsorption
Diaion HP20
antioxidant activity

How to Cite

1.
Phan Thị Diễm T, Trần Phương H, Vũ TTT, Tôn Thất H Đạt, Cường LCV. Extraction and enrichment of flavonoid and evaluation of antioxidant activity of Passiflora foetida extract. hueuni-jns [Internet]. 2025Jun.17 [cited 2025Oct.31];134(1C):109-16. Available from: https://jos.hueuni.edu.vn/index.php/hujos-ns/article/view/7753
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Abstract

Passiflora foetida L., commonly known as Lạc tiên in Vietnam, is a widely used medicinal plant in Vietnamese traditional medicine to treat diseases such as sedation, fever reduction, liver cooling, nervous breakdown, heart palpitations, and insomnia. In this study, the appropriate conditions for the extraction of P. foetida L. were determined as follows: 80% ethanol as the solvent, the solvent-to-material ratio of 10:1, the extraction temperature of 80 °C, the extraction time of 120 minutes, and the number of extractions 3 times. Activated charcoal was employed to remove chlorophyll before enriching flavonoids in the extract with Diaion HP20 resin. The enrichment process utilised 10% ethanol as the loading solvent with an extract-to-resin ratio of 16:30 (w/w). The elution with 70% ethanol increased the flavonoid content in the extract to 13.89%. Furthermore, the enriched extract exhibited strong antioxidant activity, with an IC50 value of 34.25 µg/mL.

https://doi.org/10.26459/hueunijns.v134i1C.7753
PDF (Vietnamese)

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